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"Can't start a fire without a spark"

Bruce Springsteen


D. Landschaft Berliner, K. Goldstein, G. Teichman, S. Anava, H. Gingold, I. Rieger, N. Levi, V. Pechuk, Y. Salzberg, P. Agarwal, D. Sagi, D. Cohen, E. Nikelshparg, A. Ben-Zvi, R. Zaidel-Bar, A. Miranda Vizuete, M. Oren-Suissa, O. Rechavi, A Tunable and Druggable Mechanism to Delay Forgetting of Olfactory Memories in C. elegans, bioRxiv, (2024)

I. Rieger, G. Weintraub, I. Lev, K. Goldstein, D. Bar-Zvi, S. Anava, H. Gingold, S. Shaham, O. Rechavi. Nucleus-Independent Transgenerational Small RNA Inheritance in C. elegans. Science Advances, (2023)


Y. Yovel, O. Rechavi, AI and the Doctor Dolittle challenge. Current Biology, (2023)


M.M.L. Knott, O. Rechavi, Transgenerational inheritance of engineered cytosine methylation in mice. Cell Research, (2023)


O. Rechavi, P Tomancak. Who did what: changing how science papers are written to detail author contributions. Nature Reviews in Molecular Cell Biology, (2023).


R. Haque, S. P.  Kurien, H. Setty, Y. Salzberg, G. Stelzer, E. Litvak, H. Gingold, O. Rechavi, M. Oren-Suissa, Sex-Specific Developmental Gene Expression Atlas Unveils Dimorphic Gene Networks in C. elegans, bioRxiv (2023) 


G. Teichman, D.  Cohen, O.  Ganon, N.  Dunsky, S.  Shani, H.  Gingold, O.  Rechavi RNAlysis: analyze your RNA sequencing data without writing a single line of code. BMC Biol 21, 74 (2023)

C. Kiang Ewe O. Rechavi  The third barrier to transgenerational inheritance in animals: somatic epigenetic resetting. EMBO reports e56615 (2023)


F. Bernard, D. Dargère, O. Rechavi,  D. Dupuy. Quantitative analysis of C. elegans transcripts by Nanopore direct-cDNA sequencing reveals terminal hairpins in non trans-spliced mRNAs. Nat Commun. 14, 1229 (2023). 


I.Toker, I.Lev, Y.Mor, Y.Gurevich, D.Fisher, L.Houri-Zeevi, O.Antonova, L.Hadany, S.Shaham, O.Rechavi. Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans. (2022) Dev Cell.

X. Chen , O. Rechavi Plant and animal small RNA communications between cells and organisms. (2022)  Nat Rev Mol Cell Biol.

L.Houri-Ze’evi, G.Teichman, H.Gingold, O.Rechavi. Stress Resets Ancestral Heritable Small RNA Responses. (2021) eLife. 

Houri-Ze’evi L, Korem Kohanim Y, Antonova O, Rechavi O. Three Rules Explain Transgenerational Small RNA Inheritance in C. elegans. (2020) Cell.

S.Anava, M.Neuhof, H.Gingold, O.Sagy, A.Munters, E.M.Svensson, E.Afshinnekoo, D.Danko,  J.Foox, P.Shor, B.Riestra,  D.Huchon, C.E. Mason, N.Mizrahi, M.Jakobsson, O.Rechavi. Illuminating Genetic Mysteries of the Dead Sea Scrolls. (2020) Cell. (selected for the cover).



Posner R#, Toker IA#, Antonova O, Star E, Anava S, Azmon E, Hendricks M, Bracha S, Gingold H, Rechavi O. (2019) Neuronal Small RNAs Control Behavior Transgenerationally. Cell. 
# Equal contribution
In the media: Haaretz, Ynet. See the F1000 and The Scientist Highlights



Lev I#, Toker IA#, Mor Y#, Nitzan A, Weintraub G, Antonova O, Bhonkar O, Ben Shushan I, Seroussi U, Claycomb JM, Anava S, Gingold H, Zaidel-Bar R, Rechavi O. (2019) Germ Granules Govern Small RNA Inheritance. Current biology.
# Equal contribution



Bracha S, Hassi K, Ross P.D., Cobb S, Sheiner L, Rechavi O. Engineering Brain Parasites for Intracellular Delivery of Therapeutic Proteins



Lev I, Gingold H, Rechavi O. (2018) H3K9me3 is Required for Inheritance of Small RNAs that Target a Unique Subset of Newly Evolved Genes. eLife.



Cohen D#, Teichman G#, Volovich M, Zeevi Y, Elbaum L, Madar A, Louie K, Levy DJ, Rechavi O. (2019) Bounded rationality in C. elegans is explained by circuit-specific normalization in chemosensory pathways. Nature Comm.

# Equal contribution



Hakimi A#, Mor Y#, Toker IA, Levine A, Markovitz Y, Rechavi O. (2017) WorMachine: Machine Learning-Based Phenotypic Analysis Tool for Worms. BMC Biology.  
# Equal contribution


Rechavi O. Lev I. (2017) Principles of Transgenerational Small RNA Inheritance in C. elegans. Current Biology.



Bar M, Rotblat B, Rechavi O. (2017). Nomad scientists and the ones left behind. eLife.



Lev I#, Seroussi U#, Gingold H, Bril R, Anava S, *Rechavi O. (2017). MET-2-Dependent H3K9 Methylation Suppresses Transgenerational Small RNA Inheritance. Current Biology.
# Equal contribution
See the dispatch review on the paper in Current Biology



*Houri-Ze'evi L, Korem Y, Sheftel H, Faigenbloom L, Toker IA, Dagan Y, Awad L, Degani L, Alon U, Rechavi O. (2016). A Tunable Mechanism Determines the Duration of the Transgenerational Small RNA Inheritance in C. elegans. Cell.

See the review in Nature Reviews Genetics

* Corresponding author



Houri-Ze'evi L, Rechavi O (2016). A Matter of Time: Small RNAs Regulate the Duration of Epigenetic Inheritance. Trends in Genetics.



Sagi D, Rak R, Gingold H, Adir I, Maayan G, Dahan O, Broday L, Pilpel Y, Rechavi O. (2016). Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes. PLoS Genet.



*Rechavi, O., Houri-Ze’evi, L., Anava, S., Goh, WS., Kerk, SY., Hannon, GJ., and Hobert, O.(2014). Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans. Cell. 

See also Leading Edge Commentary in Cell 

* Corresponding author



Rechavi, O. (2013). Guest list or black list: heritable small RNAs as immunogenic memories‏. Trends in Cell Biology. 



*Rechavi, O., Minevich, G., and Hobert, O. (2011). Transgenerational inheritance of an acquired small RNA-based antiviral response in C.elegans. Cell. 147, 1248 1256. 

See the F1000 Highlight

* Corresponding author



Rechavi, O., Kalman, M., Fang, Y., Vernitsky, H., Jacob-Hirsch, J., Foster, L. J., Kloog, Y., and Goldstein, I. (2010). Trans-SILAC: sorting out the non-cell-autonomous proteome. Nature Methods. 7:923-927. 



Rechavi, O., Erlich, Y., Amram, H., Flomenblit, L., Karginov, F. V., Goldstein, I, Hannon, G. J., and Kloog, Y. (2009). Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs. Genes & Development. 23:1971-1979.

Selected Publications



RNAlysis is a modular Python-based analysis software for RNA sequencing data that was developed in the Oded Rechavi Lab.

RNAlysis allows users to build customized analysis pipelines suiting their specific research questions, going all the way from raw FASTQ files, through exploratory data analysis and data visualization, clustering analysis, and gene-set enrichment analysis. RNAlysis provides a friendly graphical user interface, allowing researchers to analyze data without writing code.


WorMachine: Machine Learning-Based Phenotypic Analysis Tool for Worms

A three-step MATLAB-based image analysis software developed in the Rechavi Lab that allows automated identification of C. elegans worms, extraction of morphological features, and quantification of fluorescent signals.



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